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Using miR-21 Sponge in renal cancer cells to block endogenous function of miR-21, we show inhibition of phosphorylation of p65 subunit of NFκB, IKKβ and IκB, which results in attenuation of NFκB transcriptional activity.
Their endogenous function within an animal is unknown, but may involve regulating energy expenditure.
To investigate the endogenous function, we knocked down MBP-1 expression in HFF by RNA interference.
Importantly, the endogenous function and substrate(s) of PfCRT remain unknown.
The endogenous function of the family of HKT transporters and their role in Na+ transport and provision of salinity tolerance to plants has been reviewed recently [8].
Our findings regarding the palmitoylation motif GAP 1 14 in dendritic filopodia induction and synaptogenesis are not representative of the endogenous function of GAP-43.
Similar(25)
The endogenous functions of methylated/demethylated forms of PP2A in mammalian systems have not yet been explicitly tested.
In this report, we focused towards the identification of novel CypB-binding proteins in kidney, in order to: i) learn more about the endogenous functions of CypB and ii) unravel, in part, the molecular mechanisms of CsA-induced kidney toxicity.
Endogenous functions.
CYPs play important roles in human health via endogenous functions and interaction with environment.
It is not clear which, if any, endogenous functions of FUS are involved in disease pathogenesis.
Related(20)
implicit function
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