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Copeptin is a hormone of endogenous stress.
In general these proteins are expressed in response to the endogenous stress and they protect cells from injury (i.e. inhibit apoptosis) [126], [127].
Overall, these and our previous findings demonstrate the deleterious impacts of endogenous stress hormones and PGE2 on survival of leukemia-bearing animals.
RecQ helicases are thought to be involved in the maintenance and stabilization of replication forks in response to endogenous stress or exogenous DNA damage [2].
Together, these data suggest that progressive renal injury leads to a marked enhancement of TLR2 and several main endogenous stress ligands.
Although this model used a microbial ligand instead of endogenous stress molecules; it emphasizes the role extra-renal TLR4 can play in the kidney during disease.
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The study of immunological diseases is challenged by the diversity and complexity of immune responses to environmental and endogenous stresses.
Under different exogenous or endogenous stresses, such as those caused by ionizing radiation, ultraviolet (UV) radiation, DNA-damaging chemical agents, and other oxidative chemicals, genome integrity and cell viability are greatly threatened (Jackson and Durocher, 2013).
Glucocorticoids are endogenous stress-induced hormones that are produced under the control of the hypothalamic-pituitary-adrenal axis.
This recovery might either come from i) an uptake of exogenous stress-tolerant symbionts by corals or ii) a proliferation of endogenous stress-tolerant symbionts.
Additionally, studies examining oncogene activation have indicated that certain types of endogenous stresses are capable of inducing DNA damage and subsequent p53 inactivation [52].
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