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Viral gene expression may be regulated through epigenetic mechanisms, including cytosine methylation at CpG dinucleotides.
Recent work suggests that these metabolic memory prototypical changes may be regulated through epigenetic mechanisms [ 36, 37].
Moreover, the IGF2/ H19 locus is a well-studied region that is known to be regulated through epigenetic mechanisms and sensitive to environmental exposures [ 9].
The transcription of Sanzang was validated by RT-PCR and found in maize pollen, but not in leaf tissue, suggesting that retrotransposition activity possibly could be regulated through epigenetic modification.
However, ER-α expression can be regulated through epigenetic modification, for instance methylation at the promoter [ 15], by post-translational modifications, or through direct interaction with corepressor proteins that repress ER-α-mediated transcriptional activity [ 16, 17].
It is becoming increasingly clear that genes which suppress metastasis (Meadows 2012) as well as signaling pathways that inhibit metastasis (Singh et al. 2014) can be regulated through epigenetic mechanisms 6 induced by the diet and dietary constituents, including alcohol.
Similar(53)
In the present study, we hypothesized that the low expression of MHC class I and absence of MHC class II in hESCs cells was regulated through epigenetic mechanisms.
Importantly, all these genes are regulated through epigenetic pathways and account for the early flowering phenotypes of lhp1 mutant and possibly of TrAP transgenic plants as well (Gan et al., 2013).
Here we explored the possibility that cubilin (Cubn), an autosomal gene [ 25], is regulated through epigenetic mechanisms and whether such processes might have consequences on cubilin function and on the expression of its partners, amnionless and megalin.
These observations suggest the CYP3A4 is regulated through tissue specific epigenetic regulation in normal tissue.
These results strongly suggest that genes in GC16 and GC19 are regulated through the differential epigenetic activation of enhancers that contain p65 and AP-1 family member binding sites.
Related(20)
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