Sentence examples for be mediated through epigenetic from inspiring English sources

These effects may be mediated through epigenetic or genetic mechanisms.

Although the exact functional significance of these SNPs has not been clarified, biological studies have suggested that the effect of the risk alleles can influence the methylation capability and at least in part be mediated through epigenetic alterations [ 26, 27].

In addition, in this report, we show that unstable resistance to low levels of amp in E. coli can be mediated through epigenetic events, likely stochastic in nature, yet semi-stable, that result in elevated AmpC expression.

Given that the phenotypic effects of the gestational environmental interventions (nutritional supplementation and exposure to endocrine disruptors) were shown to persist into unexposed subsequent generations, this could be mediated through epigenetic mechanisms.

It is possible that other specific environmental or dietary exposures previously not known to be associated with lung function may be mediated through epigenetic changes such as Alu or LINE-1 hypomethylation.

Thus, impairments of normal development will ultimately change gene expression patterns in key metabolic pathways involved in obesity and MetS, which may potentially be mediated through epigenetic mechanisms [ 15, 16].

> Many cancers involve multiple factors like environmental factors or genetic factors with impact on interlinked biological pathways and the environmental effects are mediated through epigenetic modifications.

Since unknown mechanisms are believed to repress a large number of the OLFR genes all the time in most of the cell types, it is likely that these repression mechanisms are mediated through epigenetic modifications.

Current understanding of environmental cross-talk with genetic makeup is found to be mediated through an epigenetic interface which is associated with prominent reversible and heritable changes at gene expression level.

It has been proposed that the protective effect of folic acid may be mediated through an epigenetic mechanism, involving enhanced DNA and/or histone methylation.

This may be mediated through urethral hypermobility.