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Post synaptic density protein 95 (PSD-95) is a postsynaptic adaptor protein coupling the NMDA receptor to downstream signalling pathways underlying plasticity.
This would potentially strengthen the interpretation in terms of an underlying plasticity mechanism.
Despite considerable progress in the understanding of inducible defences, the underlying plasticity has rarely been studied at a molecular level.
Although environmental effects on hormone synthesis have been identified as a mechanism underlying plasticity in many insects, what causes hormones to become environmentally-sensitive was poorly understood.
These findings demonstrate a novel role for PI3K in regulating neuronal superoxide production, and suggest a shared signaling pathway underlying plasticity and excitotoxic death in the nervous system.
However, trial-by-trial quantification of this link in awake behaving animals is lacking, and current hypotheses regarding the underlying plasticity mechanisms have diverged from the classical parallel fiber one to the Purkinje cell synapse LTD hypothesis.
Similar(50)
Results of the present study are in agreement with these cited papers and could clarify some neuronal mechanisms that could underlie plasticity by providing observations at a scale much finer than fMRI.
Therefore, not only is response of immune cells to SNS stimuli highly context-dependent, but the nervous system itself also underlies plasticity depending on the inflammatory context.
To investigate the molecular and neural mechanisms underlying thermotactic plasticity, we previously performed a genetic screen to isolate the mutants defective in thermotactic plasticity, which were designated aho (abnormal hunger orientation) mutants (Mohri et al. 2005).
Sleep is important for learning, memory and underlying neural plasticity.
However, the mechanisms underlying this plasticity are still poorly understood.
Related(20)
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