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Exact(19)
This is an inherent property of methods that transfer annotations, since better annotated species provide more source functions.
We have therefore designed and implemented a novel tool, Genome Annotation Transfer Utility (GATU), to transfer annotations from a previously annotated reference genome to a new target genome, thereby greatly reducing this laborious task.
In the second step, a gene mapping program is used to transfer annotations from the reference to the target genome within the specific syntenic blocks.
However, progress beyond using BLAST to transfer annotations has been surprisingly slow.
For example, Sequin can be used to transfer annotations between highly similar HIV genomes that have identical gene content.
The most common and reliable methods are using homology mapping to transfer annotations to newly sequenced proteins.
Similar(41)
Reads were aligned against the zebrafish genome assembly version Zv9 and annotated using the gene transfer annotation file (GTF) Danio_rerio.Zv9.78 using the splice-site aware program GSNAP [ 42].
We routinely transfer annotation over to new genome builds when they are available.
Using RAST to transfer annotation from the 0140J reference suggested that SUB1095 was unique to 0140J.
In a significant number of cases, it may therefore be misleading to transfer annotation between orthologous miRNAs based exclusively on conservation.
Topological similarity is also used to guide network alignment algorithms that find similarly wired proteins between PINs of different species; these similarities are used to transfer annotation across PINs, e.g. from model organisms to human.
Related(16)
assignment annotations
transfer indications
transfer sets
transfer descriptions
transfer representations
transfer instructions
transfer indicates
transferred annotations
transfer demonstrates
transfer organisation
transfer organization
sharing annotations
transfers annotations
transfer suggests
transfer options
transfer fees
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