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Moreover, the uptake targeting ratio of the bi-functional GS-PEG-Apt was the highest (2.97), followed by GS-PEG/HA2-Apt (1.98) and GS-PEG (1.65).
We introduce the correct targeting ratio, R, as a tool to evaluate the performance of the IS when it comes to targeting pathogen Ag.
(C ) Spine targeting ratio (mean ± SEM ) for n = 5 15 neurons per condition from B. n.s.; p > 0.05 compared to wt-LIMK1-GFP.
(C ) Quantified spine targeting ratio for n = 30 neurons per condition from B confirm that only wt-LIMK1-myc is enriched in spines.
(D ) Spine targeting ratio (mean ± SEM) for n = 30 neurons per condition from C. * p < 0.05; n.s.: p > 0.05, ANOVA with Dunnett's post hoc correction.
(C ) Spine targeting ratio (mean ± SEM) for n = 32 neurons per condition from B. * p < 0.05, ANOVA with Dunnett's post hoc correction.
Similar(48)
To quantify spine to shaft targeting ratios, dendritic spine were identified in the GFP channel.
However this cytotoxic activity becomes moderate when effector to target ratio is low (below 5) and the co-culture duration is reduced to 90 minutes (data not shown).
After a 4 h incubation period, differentiated HL-60 cells were added apically at an effector to target ratio of 10∶1 and incubated for 3 more hours.
Splenocytes of HCT/HHD/B7.1-immunised animals were incubated with the target cells in a 50 : 1 effector to target ratio.
1-8D peptides mount more than twice higher CTL responses than the HIV peptide at a 50 : 1 effector to target ratio.
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