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Our results indicate that the YOMICS™ antibody library is a tool for systematic protein expression profile analysis that nicely complements the already available commercial antibody collections.
To enable systematic protein function interrogation in a multicellular context, we built a genome-scale transgenic platform for in vivo expression of fluorescent- and affinity-tagged proteins in Caenorhabditis elegans under endogenous cis regulatory control.
Here, we performed systematic protein interaction screens in S. cerevisiae to identify new CIA interaction partners.
Equilibrium denaturation measurements are exceptionally powerful when combined with systematic protein mutagenesis (the 'protein engineering method') [5,8,15,16].
To identify new CIA proteins we employed systematic protein interaction approaches and discovered the essential proteins Yae1 and Lto1 as binding partners of the CIA targeting complex.
Based on microarray analyses in hepatocellular carcinoma (HCC), SLC22A1/ OCT1 mRNA seems to be downregulated, but systematic protein expression data are currently missing.
Similar(48)
Systematic protein-protein interaction dataset for P. falciparum was made available by a previous study [34].
A systematic protein-protein interaction network analysis approach was presented to predict dangerous pharmacodynamic drug interactions (43).
Fission yeast (Schizosaccharomyces pombe) is a valuable model organism for which no systematic protein-interaction data are available.
In the context of a systematic protein-protein interaction network mapping effort for components of the PI3K-AKT-MTOR pathway, we screened a cDNA library from E10.5 mouse embryo and the hORFeome1.1 library with human GSK3A and GSK3B as baits.
Thus, often cumbersome strategies have to be developed, like systematic target protein mutagenesis or sub-fragment analysis.
Related(20)
exhaustive protein
regular protein
routine protein
indiscriminate protein
widespread protein
intentional protein
comprehensive protein
frequent protein
structured protein
consistent protein
structural protein
systems protein
methodology protein
consistently protein
mass protein
systematic retribution
systematic reporting
systematic process
systematic distortion
systematic blood-doping
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