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Nearby sequences such as the Shine-Dalgarno sequence in E. coli and initiation factors are also required to start translation.
Notably, Met/Ala SV sg-mRNA is unable to start translation at that site in uninfected cells or in cell-free systems and translation start at the first AUG codon.
Close inspection of the Xcv 85-10 genomic sequence neighbouring the annotated xopD gene shows that upstream of the annotated starting codon AUG, there are 6 AUG, 1 GUG and 5 UUG additional codons that are in frame and may potentially be used to start translation of the protein (Figure 1C).
From this hybridization, reverse transcriptase utilizes the double-stranded sequence as a primer to start translation.
Only when all the riboswitches' aptamers are on, ribosomes are allowed to bind the mRNA and to start translation.
In order to start translation, the initiator tRNA carrying methionine is required, and in fact, among the amino acid metabolic pathways, methionine is one of the fastest.
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And that's where the sociological view on innovation starts: translation -- or all the strategies that are involved in redefining actors and their goals in ways that make a particular new technology, idea or content acceptable, legitimate, or even natural.
However, there is no report that any of the animal NOS mRNAs starts translation at a non-AUG codon.
Another important caveat for the reported activity estimates is that they are based on the assumption that once a ribosome starts translation, a functional protein will always result.
One of the sequences is 846 bp after the start of translation, and other is 2371 bp after the start of translation.
*Based on NCBI NM002394 numbering; 1st methionine (start of translation) = 225.
Related(20)
start transcript
initiating translation
start transfer
start localization
start expression
start transcription
commencing translation
start conversion
start translators
start interpreting
start application
start rereading
start translate
initiated translation
launched translation
start splitting
start decreasing
start pause
start recovery
start constructing
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