Sentence examples for mutations would cause from inspiring English sources

And it's not clear how the mutations would cause either disease.

With disrupted structures, mt tRNAs mutations would cause defective translation and impaired mt protein synthesis, leading to defects in OXPHOS systems.

It is found that most multidrug-resistant mutations have only a modest or moderate effect on substrate peptide binding, although these mutations would cause a large free energy loss in PR inhibitor binding.

By showing how sexual reproduction and other features of Mendelian genetic systems implied that natural selection of random mutations would cause both adaptation and speciation, Fisher (1930) provided the impetus for the 'modern evolutionary synthesis' between genetics and evolution, although it took decades for the full magnitude of his achievement to sink in.

What Gahl is looking for is the whole package: a defect in the patient's DNA that points to a specific genetic mutation; evidence that explains how that mutation would cause the patient's symptoms; and a clinical demonstration that the protein — or other chemicals — made by the gene is missing or defective, and that its derangement accounts for the symptoms.

Because each cell contains hundreds to thousands of mitochondria, many scientists had assumed that a mutation would cause trouble only if mitochondria containing it greatly outnumbered those that didn't.

We next investigated if the U6atac mutation would cause systematic effects on the splicing of U12-type intron-containing genes by plotting the exon array data of those genes and comparing this to the structures of individual genes.

It seems likely that the presence of this mutation would cause no cleavage by the 5' -3' exonuclease activity of the Taq polymerase and therefore no liberation of the fluorescent reporter, making quantification impossible [26], [27].

Therefore, V263M mutation would cause very limited influence to the folding and stability of the protein.

In vitro splicing assay demonstrated that this mutation would cause skipping of exon 3 leading to a protein (if produced) lacking the transmembrane MC2R interacting domain.

If the AOP2-3 allele is transcribed, the 5 bp mutation would cause the introduction of a series of stop codons in the transcript, which may have a negative effect on mRNA stability [ 41].