Sentence examples for mutations would affect from inspiring English sources

In another aspect, although there have been achievements in engineering POx for better thermostability and catalytic efficiency (Bastian et al. 2005; Heckmann-Pohl et al. 2006; Masuda-Nishimura et al. 1999), it is not known how the mutations would affect the behavior of the pyranose oxidase in breadmaking.

Before beginning this study, it was not possible to predict which mutations would affect the catalytic properties and the susceptibility of the interface Cys to sulfhydryl reagents.

We generated a double mutant Pak1 (and8Q and T219E [LC8mut-Pak1]; see Fig. 1B) to abrogate LC8 binding and tested whether these mutations would affect Pak1 nuclear import.

Since HIV-1 RT is incorporated into the virion in the form of Pr160gag-pol, which is transported to cell membrane where the virus is packaged, through interaction with Pr55gag [27]–[30], we thus investigated whether the mutations would affect Pr160gag-pol expression and transportation.

The mutations would affect also healthy cells, but would not drastically injure them.

Changes in the ATP levels within neurons such as those that may occur in response to accumulating mitochondrial DNA mutations would affect the extrusion of calcium.

Our prediction, based on the AML data, would be that the V391I RING finger domain mutation would affect the E3 activity.

Since NANOS3 has been shown to act in the cell nucleus [ 37], studies were performed to investigate whether the p.Glu120Lys mutation would affect intracellular localization.

Since PLD α 1 expression was enhanced in GmMYB73-transgenic Arabidopsis plants, we examined whether PLD α 1 mutation would affect lipid accumulation.

The R175H mutation would affect all known splice variants of TP53 (Bourdon et al, 2005) and has been shown to be transactivation defective (Soussi and Wiman, 2007).

We did not directly assay whether this specific mutation would affect splicing, but the patient tested mutation negative for COMP, MATN3, COL9A1, and COL9A3, and the c.186+4a>c mutation co-segregated with the affected mother and brother of the proband.