Sentence examples for mutations would impact from inspiring English sources

Our above analyses have relied on simple epidemiological models to gain intuition for how circulating sublethal deleterious mutations would impact patterns of influenza A/H3N2's antigenic evolution.

The increased flexibility observed in MD simulations of the loop due to polyglycine mutation would impact the rate only if it affects the reactive interface of the general base and the substrate.

We appreciate that the referees are interested in how deleterious mutations would further impact the evolutionary dynamics of H1N1 in humans and H3N2 in pigs.

The current study aimed to test whether NOTCH1 mutations and additional molecular abnormalities would impact T-ALL outcome in a series of 138 T-ALL paediatric cases.

Many AML types are characterized by mutations in C/EBPα and RUNX1, which would impact many of the binding sites described here.

The location of the mutation upstream of the C-terminus would impact both BBS3 and BBS3L, as this region is identical between the two isoforms (Fig.  1B).

However, it could also be due in part to higher mutation rates of microsatellites relative to SNPs, which would impact upon levels of LD (reviewed in [ 37]).

If some HARs regulate human-specific social and behavioral traits, then mutations would likely impact cognitive and social disorders.

Thus, a prediction based on our structural analysis is that class 1 mutations would have a greater negative impact on pVHL-HIF-2α interaction than class 2 mutations.

The structures of MFS transporters [4 29] show that substrates bind invariably in the V-shaped cleft between the N-terminal and C-terminal halves of the protein, so if this also applies to TetA(B), then the model suggests that none of the mutations would have had a significant direct impact upon the affinity of tetracycline binding.

Many of the acquired suppressor mutations would not have necessarily been predicted to significantly impact kinase activity.