Sentence examples for mutations are sometimes from inspiring English sources

Patients who have an elevated probability of carrying germline susceptibility gene mutations are sometimes detectable [ 19, 20].

Because NHEJ-dependent repair ignores DNA deletion or insertion in DSB sites, frame-shift mutations are sometimes created [ 46].

GOF mutations are sometimes related to reduced furin cleavage of PCSK9 [ 52] while LOF-mutations relate to lack of PCSK9 phosphorylation and subsequent increased proteolysis [ 45].

We conclude that, although germline E-cadherin mutations are sometimes found in familial gastric and colon cancer, they are not frequently involved in families in which gastric cancer appears to segregate as a part of an inherited predisposition to primary breast cancer.

We conclude that, although germline E-cadherin mutations are sometimes found in familial gastric and colon cancer, they are not frequently involved in families in which breast cancer appears to segregate as a part of an inherited predisposition for gastric and colon cancer.

Compound heterozygosity, exhibiting both a retrotransposonal mutation and a point mutation, is sometimes seen and generally exhibits more severe pathologies (13– 13).

In addition, we are able to determine whether a mutation is sometimes, rather than always or never, detectable because it is simulated in the read sets of hundreds of samples; for example, this could occur in a particular genetic background with a low-frequency in cis variant that interferes with alignment of reads containing the mutation.

We have changed this to read "… with stabilizing mutations permitting otherwise inaccessible destabilizing mutations which are sometimes of adaptive value".

Our results paint a coherent portrait of epistasis during nucleoprotein evolution, with stabilizing mutations permitting otherwise inaccessible destabilizing mutations which are sometimes of adaptive value.

Note that these numbers are only a lower bound on the fraction of codon mutations sampled by the mutant viruses even synonymous mutations to influenza are sometimes strongly deleterious (Marsh et al., 2008), and so some of the missing synonymous codon mutations may have been introduced into mutant viruses but then purged by purifying selection.

The peptide variants resulted from DNA mutation or mRNA alternative splicing are sometimes also considered as novel peptides.