Sentence examples for mutations and poor from inspiring English sources

Mesothelin overexpression in lung adenocarcinomas correlates with the presence of activating KRAS mutations and poor prognosis.

However, the association between KRAS mutational status and prognosis is controversial for patients with metastatic CRC that have not been treated with anti-EGFR antibodies, with some studies reporting a link between KRAS mutations and poor prognosis [15] and some reporting no association [12].

Additional studies have confirmed the association of KRAS mutations and poor prognosis [ 30, 32, 36- 38].

Interestingly, associations have been made between D310 mutations and poor disease-free survival, a late onset age, and estrogen and progesterone-negative breast cancers (Tseng et al, 2006).

The good predictive value of EGFR mutations and poor predictive value of KRAS mutations with regard to EGFR TKI treatment was not reflected in terms of prognosis in our patient cohort.

Two studies in the literature are in agreement with this result (Yamada et al, 1998; Theodor et al, 2000), but another one found a statistically significant relation between circulating DNA KRAS2 mutations and poor prognosis (Castells et al, 1999).

If the SSM is correct, individuals who become schizophrenic patients will tend, on average, to have lower genetic fitness (e.g., more deleterious mutations) and poorer developmental conditions (e.g., nutritional deficiencies, infections, and so on) compared with those who do not.

Some reports imply association of BRAF/ NRAS mutations and poorer prognosis in the metastatic setting.

CD24 mRNA overexpression correlates strongly with p53 gene mutation and poor HCC differentiation [ 18].

Most of the false results obtained related to two samples with a p.V600K mutation and poor DNA quality.

A recent publication detailing the University of California, San Francisco experience has called into question the relationship between the BRAF mutation and poor clinicopathologic factors.