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To detect the associated mutations and identify novel allelic variants in the candidate genes, representative samples were collected from the breeding tract of indigenous goat breeds varying in prolificacy and geographic distribution.
Model studies of the subtype B and non-subtype B integrases are still required to compare their susceptibility to antiretroviral drugs, evaluate the significance of resistance mutations and identify the impact of natural polymorphisms on the level of enzymatic reactivity.
Roche provided raw sequence data for eight strains and tables of differences between each strain and the non-parental reference strain MG1655 (∼350/strain), which we analyzed manually to find known mutations and identify new ones.
This, along with the associated epidemiology, enables one to look beyond the discovery of driver mutations, and identify predictive signatures in HNSCC.
To determine the existence and distribution of CCR2 gene mutations and identify polymorphic groups of the coreceptor gene in the population, a cross-sectional study was conducted to analyze the differences in allelic frequencies of CCR2-64I among HIV-1 seropositive individuals.
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Like Gollob, she's intrigued by somatic mutations and identified one a few years ago in an Alzheimer's patient.
He developed a statistical method to identify such clusters of mutations, and identified several cases of strong clustering of mutations in a comparison of human and chimpanzee genes.
We have manually catalogued the annotated mutations and identified 118 mutation instances that are annotated in the corpus.
In conclusion, this report describes a rapid method for identifying drug resistance mutations and identifying cotreatment strategies that prevent the selection and evolution of resistance phenotypes.
Last, we confirmed the independent prognostic relevance of ASXL1 gene mutations and identified the novel adverse prognostic impact imparted by CBL mutations.
We mapped several mutations and identified alleles of Bicaudal-D, lethal(2) giant larvae, kuzbanian, GDP-mannose 4,6-dehydratase, tho2, and eiF4A.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com