Sentence examples for mutation which enhances from inspiring English sources

A pUC18 derivative vector, namely pML005, was constructed by site-directed mutagenesis to obtain a plasmid that displays a previously described mutation which enhances its stability in L. pneumophila [18] and allows complementation experiments in derivative strains.

An induced null mutation in the calcium-proton antiporter cax1 in A. thaliana is the only characterized mutation which enhances survival on soils with low Ca∶Mg ratios [18].

Conversely, the B-RafE586K mutation, which enhances dimerization and possibly allosteric transactivation, increases Erk signaling [23].

Besides the prevalent V599E mutation, which enhances kinase activity, there are three other classes of mutations whose functional consequences are less clear (Mercer and Pritchard, 2003).

Following the same line of thought, it is more difficult to explain the pathogenic effects of the G2019S mutation which enhances kinase activity and did not show any destabilization effects on the protein in the kidney of mutant mice.

Paradoxically those that also carried the furT41A mutation, which enhanced resistance in other contexts, were even more Mtz-sensitive (50R,64S).

This notion was further supported by the converse effect of the T3232A mutation, which enhanced Rad51 binding.

Tumor growth is caused by the acquisition of driver mutations, which enhance the net reproductive rate of cells.

Drug-resistance mutations can often be categorized as either primary mutations, which directly decrease the susceptibility of the virus to an ARV, or accessory mutations, which enhance viral fitness and further decrease susceptibility.

In a family of HBM cases due to activating low-density lipoprotein receptor-related protein 5 (LRP5) gene mutations, which enhance osteoblast activity, radiographs have shown widened long bones and cortices [2].

The presence of sweeps in regions harbouring genes associated with reproductive processes may be a result of the selection for mutations which enhance reproductive rate or that result in improved calving ease.