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Exact(7)
Not all genetic disorders are familial, however, because the mutation may arise for the first time during the formation of the gametes or during the early development of the fetus.
Compared to other animals (and with notable exceptions), vertebrates have longer lives and bigger bodies, providing a bigger pool of cells over longer time periods in which an oncogenic mutation may arise.
The initial mutation may arise de novo or be inherited from a parent.
The third possibility is that a large beneficial mutation may arise in viruses that have many harmful mutations.
Changes in KM upon mutation may arise from changes in the substrate dissociation constant and/or from changes in other microscopic rate constants.
Therefore, the probability that the mutation may arise as somatic mutation on the allele carrying SNP28 independently of the founder mutation is extremely low.
Similar(53)
Such mutations may arise during triclosan selection.
Furthermore, compensatory mutations may arise, which lead to recovery of fitness, although this requires further viral adaptation.
BRAF mutations may arise in certain cells that express high levels of B-Raf as a result of hormonal stimulation.
Risk mutations may arise de novo, but may also be inherited, as is the case for 75% of individuals with 15q13.3 microdeletions.
Therefore, mutations may arise more rapidly and be selected for more quickly in a low androgen environment despite the lower cell count.
Related(20)
mutant may arise
variation may arise
shift may arise
transfer may arise
mutation may need
evolution may arise
mutation may exist
mutation may develop
mutation may cause
mutation may result
mutation may work
mutation may serve
mutation may be
mutation may predict
mutation may drive
mutation may lie
mutation may affect
mutation may enhance
mutation may increase
mutation may date
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