Sentence examples for mutation may lie from inspiring English sources
The markers, which are like milestones along each chromosome, have a fixed position and so can be used to define a region of the chromosome where a schizophrenia-causing mutation may lie.
The discrepancy between the normal enzyme activity of complex II vs the decreased complex I and IV enzyme activities in the sample with the A3243G mutation may lie partly in the fact that the latter complexes are involved in proton pumping, whereas the former is not.
Such a difference between Q344ter and K296E mutations may lie in the degree of phosphorylation and the stability of the rhodopsin/Arr1 complex: K296E cannot bind 11-cis retinal and exists in an active conformation as it is synthesized [56].
Furthermore, many of these mutations may lie within genes already implicated by association studies.
Unpublished simulations using beef cattle genotypes shows that causal mutations may lie in regions upstream or downstream of the window that has the strongest association.
Clinical applications are also somewhat limited due to the fact that many RP genes are still unknown, and mutations may lie outside of commonly tested regions.
In analyzing putative human Msx mutations, the greatest challenge may lie in distinguishing neutral genetic variation from mutations that are likely to have significant clinical consequences in multifactorial disease cases [ 44].
Alternatively, the mutation in mei-218 may lie in the regulatory regions.
The explanation may lie in mutations.
Rather, control may lie in mutations at a few key loci that, because of their position in a pathway (e.g. branch points [ Eanes 1999]), can affect fitness.
Other models propose that the microenvironment is the driving force of the benign lesion evolution into full invasive tumors; Gatenby and Gillies even speculate that the origin of cancer may lie not in mutations within epithelial cells, but within acquired or somatic mutation changes in the mesenchymal cells that control tissue structure [ 41].
