Sentence examples for mutation may serve from inspiring English sources

In addition, our study suggests that Met to Gln mutation may serve as an important tool to understand Met oxidation.

Genes identified as CISs in this manner represent strong candidates whose mutation may serve as a driving event during cancer development.

The detection of a ret/PTC-1 rearrangement in Case 7 (Hürthle cell variant of papillary carcinoma) suggests that GRIM-19 mutation may serve as a predisposing alteration for the occurrence of tumours with cell oxyphilia.

Given the high prevalence and stability of these mutations over the course of disease, NPM1 mutations may serve as ideal targets for minimal residual disease (MRD) assessment in AML.

These mutations may serve as useful markers in predicting HCC development.

Therefore, changes in the ITGA3/CD9 and ITGB4/JUP levels as phenotypes due to a variety of mutations may serve as common indicators of biological malignancy of SCC.

Recently, mitochondrial DNA (mtDNA) depletion- and mutation-induced oxidative stress have been shown to be linked to increased tumourigenicity and an invasive phenotype, suggesting that mtDNA mutations may serve as markers for cancer progression (Amuthan et al, 2001).

This finding supports our hypothesis that SNPs predictive of EGFR pathway mutation status may serve as informative biomarkers for predicting cetuximab response.

In comparison, recent studies in Arabidopsis reveal a tendency for initial length mutations to engender additional nearby length mutations that may serve to offset deleterious effects of the first indel (Long et al. 2013).

Given the prominent role of the transient outward current (Ito) in BrS pathogenesis, we hypothesized that rare gain-of-function mutations in KCND3 may serve as a pathogenic substrate for BrS.

We propose that analogous to germline genetic mutations constitutive epimutations may serve as the first hit of tumor development.