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Exact(5)
The relatively high frequency of the R14W mutation may account for the known increased prevalence of CDA II in Italy.
14, 15 Depending on the APC resistance functional assay used and the cut-off values for defining an abnormal result, the factor V Leiden mutation may account for 85 95% of patients with APC resistance.
Lynch et al. (2006) have pointed out that nonselective forces such as drift and mutation may account for major differences in organelle genome structure among animals, plants, and unicellular eukaryotes.
It is likely that the cleavage and/or truncation of the intact envelope protein products due to mutation may account for the presence of the apparently smaller than the expected size (~70 kD).
Instead, according to the recently published structural analyses of the Cx26 gap junction channel, the localization of the mutation may account for an impairment of biochemical coupling, because the molecular cut-off size and charge selectivity of the channel are influenced by the properties of N-terminal amino acid residues (7).
Similar(55)
In the end, these kinds of mutations may account for 20 to 30 percent of cases of autism, and perhaps schizophrenia, some experts said.
These findings taken together with the established role of EPHB receptors in colorectal cancer, prompted us to hypothesize that germline EPHB2 mutations may account for at least a fraction of the genetic alterations underlying the unexplained portion of hereditary colorectal cancer, and may represent a new cancer syndrome causing genetic predisposition to colorectal and prostate cancer.
Small changes in the expression of ion channels may significantly influence the temporal selectivity of neurons [43], suggesting that few mutations may account for the differences in call recognition mechanisms observed in Neoconocephalus and other insect and anuran systems [20], [44].
Somatic point mutations may account for only a fraction of the genetic alterations required for tumorigenesis.
De novo mutations may account for a high proportion of Mendelian disorders.
Here, we hypothesized that de novo mutations may account for a proportion of these early-onset, sporadic cases.
Related(20)
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mutation may lie
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mutation may increase
mutation may date
mutation may exist
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