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Exact(6)
S315T-MtKatG mutation is widely reported for INH resistance.
However, three recent studies have shown that the polymorphism described in the first paper as a causal mutation is widely shared by non-preeclamptic women from various populations [3] [5].
Furthermore, the TP53 gene mutation is widely known as an important determinant of impaired chemosensitivity [ 2].
TP53 gene mutation is widely known as one of the determinants of impaired chemosensitivity.
Thus, a glutamine to leucine mutation is widely assumed to generate the active conformation of these proteins.
At that, artificial substitution of serine to aspartate and glutamate, called phosphomimetic mutation, is widely used to confirm phosphorylation of serine [ 26, 27].
Similar(54)
Of the 142 mtDNAs analyzed, 74 were categorized into macro-haplogroup M, and the rest 68 pedigrees' mtDNAs were assigned to macro-haplogroup N. mtDNA haplogroup distribution analysis showed that 1555A>G mutation was widely dispersed among 11 major Eastern Asian haplogroups D, M7, M8, M10, M11, G, F, B, R, A and N9 (Fig. S2 and Table S2).
Parasites carrying the 581G mutation are widely distributed in Tanzania (figure 5) and elsewhere in Africa (figure 6).
Genetic testing to identify BRCA1/2 mutations is widely available and commonly employed.
Overall, MxA single-point mutations are widely spread in different human cancers, and MxA mutates more frequently in colorectal cancer according to current data.> -wrap-foot> aR655C mutation was discovered in colorectal cancer in two individual sequencing projects We then checked the conservation level of the amino acid residues mutated in cancers.
Activating mutations in one allele of an oncogene (heterozygous mutations) are widely believed to be sufficient for tumorigenesis.
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