Sentence examples for mutation analysis demonstrated from inspiring English sources

Mutation analysis demonstrated that Ile529 and Asn560 on E2s were the most crucial residues for its interaction with 8H3, and they were the key sites to maintain the epitope of 8H3.

The luciferase activity assay and point mutation analysis demonstrated that the downregulation of FOXO3a was mediated by miR-96 through the FOXO3a-3'UTR.

Furthermore, mutation analysis demonstrated that CDT toxicity correlated with phosphatase activity and that CDT-induced G2 arrest correlated with intracellular levels of PI-3,4,5-P3 PI-3,4,5-P3 PI-3,4,5-P3

Mutation analysis demonstrated that simultaneous mutation of both RAM PY-NLSs causes a localization defect indistinguishable from the GFP control.

Collectively, the mutation analysis demonstrated that PML/RAR α repressed the transactivation of the CDKN2D promoter through the ER8 site located at −368 bp to −349 bp.

The luciferase activity assay and point mutation analysis demonstrated that the downregulation of FOXO1 and p27Kip1 was mediated by miR196-a through the FOXO1-3′-UTR and the p27-3′-UTR, respectively.

Thus, the data from the point mutation analysis demonstrate that the function of the SARE in hypoxia and anoxia is dependent on a highly inducible antisense HBS.

Homology modeling and mutational analysis demonstrated a single mutation in human FFA2 of C4.57G resulted in a human FFA2 receptor with ligand selectivity similar to the bovine receptor.

Moreover, our mutational analysis demonstrated that PTEN expression loss was associated with PTEN-truncating mutations (P=0.03).

Within the critical genomic region, sequencing did not reveal a coding mutation whereas expression analysis demonstrated significant up-regulation of grainyhead-like 2 (Grhl2) in Axd mutant embryos.

Breast cancer subgroup analysis demonstrated mutation of at least one of the three genes with the highest frequency in HR+/ERBB2- tumors (133/289; 46.0%).