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NO could either affect bacterial viability directly by affecting multiple targets such as mycobacterial DNA and copper metabolism [41] [43], target mycobacterial virulence factors [23] or act as second messenger [24].
The molecular mechanism of WM130 may possibly involve multiple targets, such as blocking TGF- β/Smad and Ras/ERK pathways.
Approaches that employ multiple targets such as the chaperone and proteasome system or chaperones and the CMA pathway seem reasonable.
Fabricating multicolor assays based on UCNPs is of particular importance for bioimaging and real-time tracking of multiple targets, such as the systems of proteins and genes.
Multiplexed imaging enables real-time tracking of multiple targets such as proteins and genes, which are important for bioanalysis, clinical diagnosis, as well as for the therapeutic treatments.
The potential polypharmacological effects of all active compounds in this work are involved in the modulation of multiple targets, such as the two highly connected nodes M30 (quercetin, degree=39, betweenness=0.17509) and M34 (luteolin, degree=35, betweenness=0.11984).
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When targets' regions have merged together, multiple moving targets are regarded as a whole target to track for the moment, while when splitting multiple moving targets, feature matching is used to establish corresponding relationship of multiple merged targets, such an example of tracking three human targets in an outdoor scene is shown in Fig. 5.
Even though current experiments have no supports for such predictions targeting to mitochondria now, that won't be proper to lead to the conclusion that there doesn't exist multiple targets for such proteins because we may disregard the dynamic properties of them.
Our methodology could be applied to the assessment of a variety of microbicide gel formulation attributes, for those targeting HIV only or those with multiple prevention targets, such as unintended pregnancy, HIV, and other infections.
In normal cells, NFκB is activated by various stimuli, such as pathogens and pro-inflammatory cytokines, and controls the expression of multiple target genes, such as TNF, IL6, and MMP9[ 10- 13].
Moreover, the approach is generic in the sense that it can be used to define information models for multiple target technologies, such as OPC UA, MTConnect and others.
Related(20)
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