Sentence examples for multiple target tissues from inspiring English sources

Treatment with rhBCL2A1 or rhBCL2 protein protects mice from sepsis by reducing apoptosis in multiple target tissues, demonstrating an unexpected, potent activity of extracellularly administered BCL2 BH4-domain proteins.

Bioavailable testosterone in acts upon multiple target tissues and completes the feedback loop inhibiting GnRH and LH secretion.

It has been proposed that MSCs contribute to tissue and organ repair and have therapeutic potential in the regeneration or repair of multiple target tissues [ 23].

All laboratories were successful in detecting weight increases in multiple target tissues after treatment with MT and TREN, as well as weight decreases of multiple target TP-stimulated tissue weights with VIN, DDE, and FIN.

Although GH itself is able to trigger biological responses in multiple target tissues, the most important 'downstream' target of GH is the liver, where GH stimulates IGF-I secretion through the activation of the hepatic GH receptor.

27– 29 It may be argued that in future the further increase in the number of susceptibility genes identified for metabolic disorders will lead to considerable improvement of the predictive power of genotypic biomarkers in polymorphism and gene combinations of increasing complexity, affecting multiple target tissues and pathogenic pathways.

The action of PPARβ/δ involves multiple potential target tissues (11), appearing to increase HDL cholesterol levels and to reduce postprandial triglyceride levels by increasing their clearance (12), leading to potentially beneficial changes in fasting triglyceride, apoB, LDL cholesterol, insulin, liver fat, and urinary inflammatory markers (13).

As pleiotropic hormones, vasoinhibins act in multiple target organs and tissues.

Leptin receptors (LEPR) form homodimers that, in general, act by signaling via the Janus kinases to regulate multiple events in target tissues [ 2].

This phenomenon was observed in RA, in psoriatic arthritis, in ankylosing spondylitis, in uveitis, and in multiple sclerosis, where target tissues were also enriched in CMV-specific and EBV-specific T cells [ 89].

Interestingly, with an increasing requirement for multiple target sites the tissue-specific listing "Nervous System Development and Function" rises through the ranking of functions, from 11th to 2nd position.