Sentence examples for multiple target organs from inspiring English sources

Taken together, these data indicate that treatment with rhBCL2 or rhBCL2A1 protein reduces sepsis-induced apoptosis in multiple target organs.

Neural crest cells arise at the border of neural and non-neural domains, and subsequently migrate to multiple target organs [10].

As pleiotropic hormones, vasoinhibins act in multiple target organs and tissues.

The last large-scale evaluation of BPA's potential carcinogenicity in multiple target organs was a National Toxicology Program (NTP) 2-year chronic feed study conducted in 1982, which employed doses ranging from 1,000 to 10,000 ppm BPA.

The past decade has brought evidence of benefit of androgen treatment of hypogonadal men on multiple target organs and the recent studies show short-term beneficial effects of testosterone in older men that are similar to those in younger men.

Leptin (Baumann et al., 1996; Vaisse et al., 1996; Villanueva and Myers, 2008) as well as various cytokines such as IL-6, TNF and IL-1β (Yu et al., 2009; Grivennikov and Karin, 2011) have been suggested as potent activators of STAT3 signaling in multiple target organs.

Since then, the use of aspirin has been inversely associated with multiple target organ malignancies (Cuzick et al, 2009).

However, patients with autosomal dominant PHA1 generally have much milder symptoms of having renal PHA than those with autosomal recessive PHA1 which shows multiple target organ unresponsiveness to mineralcorticoids such as sweat and salivary glands, colon and kidney [ 2].

One weakness of benchmarks is that compounds are evaluated individually, whereas real life exposure scenarios involve multiple exposure routes and multiple compounds acting upon target organs and/or systems.

Hormesis does not accommodate multiple toxic end points, target organs or mechanisms.

Can typical single end point hormesis accommodate multiple toxic end points, target organs, and toxicologic mechanisms?