Sentence examples for multiple proinflammatory genes from inspiring English sources

During infection, NF-κB positively regulates the expression of multiple proinflammatory genes [31].

Within the same specimens, HERV-W env transcript levels were correlated with the expression of multiple proinflammatory genes (p<0.05).

Additionally, it potently controls the expression of multiple proinflammatory genes involved in the development of insulin resistance (108).

The examination of a pairwise correlation of gene expression revealed coordinated upregulation of multiple proinflammatory genes in myeloid cells.

One that is known to activate multiple proinflammatory genes is nuclear factor-κB; we know that patients who have greater activation of NF-κB tend not to survive.

Activation of NF-κB serves to induce the expression of multiple proinflammatory genes, many of which are also regulated by HIF-1α [ 78, 111].

In addition to the HMGB1 TLR4 signaling cascade, multiple other proinflammatory genes are increased and have been detected postmortem in the brains of alcoholics.

This plethora of proinflammatory genes upregulated at immunosenescence is consistent with multiple observations on the low-level inflammatory status commonly found in the elderly, and also associated with poor prognosis in longitudinal studies (Wikby et al., 2006).

Interestingly, S. flexneri uses the T3S apparatus to secrete several effectors that alter multiple signaling pathways in infected cells and reduce the expression of proinflammatory genes [19].

Using the resultant TNFR1 model with robust parameters, we performed simulations of multiple in silico KOs to determine an optimal target that suppresses, but not abolishes, proinflammatory genes.

In addition, the model is dependent on multiple proinflammatory cytokines including TNF and IL-1, as assessed by specific anti-cytokine therapy and gene expression analysis [ 49, 50].