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The investigation shows that the multiple marker approach successfully prevents numerical coalescence of interfaces and adequately captures the effect of surface tension.
The model included the diallelic DGAT1 effect and the QTL transition probability estimated for each chromosomal position by a multiple marker approach.
In addition, we show evidence that the ErbB/PI3K/Akt/ NF- κB signalling pathway is involved in prostate cancer progression and that a multiple marker approach identifying active signalling pathways may be prognostically more relevant than single markers.
Cytochrome c oxidase subunit 1 (COI) has very low levels of polymorphism and has limitations as a useful tool for delimitating coral species [ 42]; however, it was informative when combined and compared in a multiple marker approach.
The correlation was significantly improved from r = 0.47 using the single markers PRO-C3 to r = 0.62 for model A. A multiple marker approach combining the MELD score for liver function and the two novel ECM serological markers for fibrosis, model B, increased the correlation with HVPG to a higher level than observed for MELD alone (r = 0.75).
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In brief, using a multiple marker-based approach, the probability of inheriting a particular allele at a particular marker location is calculated and used to estimate the information content for each marker.
In order to take into account the LD between markers, we used in addition to a single marker approach a multiple forward regression approach to identify based on the above described PK model those marker combinations, which explain best the genotypic variation.
One way to partially reduce the costs associated with multiple marker testing is a stepwise approach.
In this study interval mapping with multiple-marker regression approach was extended to analyse multiple chromosomes simultaneously.
In contrast, the RT-PCR approach seems to be more sensitive and allows easy multiple marker testing [ 39, 40].
Among all available mapping methods, the multiple-QTL approach is particularly suitable for complex trait analysis since it uses simultaneously multiple marker intervals with possible inclusion of epistasis terms in QTL mapping model [ 23].
Related(20)
multiple indicator approach
multiple marker method
multiple loci approach
multiple scenario approach
multiple imputation approach
multiple outputation approach
multiple access approach
multiple marker interval
multiple marker profile
multiple marker regression
multiple period approach
multiple regression approach
multiple integration approach
multiple comparison approach
multiple mode approach
multiple barrier approach
multiple perspective approach
multiple behaviour approach
multiple marker model
multiple sampling approach
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