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The method is similar to that used by Tian et al. (2011) on maize except that our association analysis, like that of Lafarge et al. (2017), was based on a single marker model rather than a multiple marker model.
The final multiple marker model included miR-15a, -27a, and -34a.
The receiver operating characteristics curves for miR-15a and for the multiple marker model are shown in Fig. 3.
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Multiple marker sets and models are currently available for assessing foot and ankle kinematics in gait.
Multiple marker sets and models are currently available for assessing pelvic kinematics in gait.
We then checked to see if model fit (measured by adjusted R) would be improved by any combination of multiple markers in the model.
The correlation was significantly improved from r = 0.47 using the single markers PRO-C3 to r = 0.62 for model A. A multiple marker approach combining the MELD score for liver function and the two novel ECM serological markers for fibrosis, model B, increased the correlation with HVPG to a higher level than observed for MELD alone (r = 0.75).
MIM uses multiple marker intervals concurrently to fit several potential QTL in the model, thereby increasing power and precision (Kao et al. 1999).
Among all available mapping methods, the multiple-QTL approach is particularly suitable for complex trait analysis since it uses simultaneously multiple marker intervals with possible inclusion of epistasis terms in QTL mapping model [ 23].
A multiple marker Coupled Level-Set/Volume-of-Fluid (CLSVOF) method for droplet-laden flows has been extended with a physical model to accommodate coalescence and breakup of the droplets.
The model included the diallelic DGAT1 effect and the QTL transition probability estimated for each chromosomal position by a multiple marker approach.
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