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Pauline and Paul Poe had three children born with multiple congenital abnormalities; all three had died shortly after birth.
These agents have antifolate effects and other antifolate agents can induce multiple congenital abnormalities, neural-tube defects, cardiovascular, and other malformations in animal experiments and in humans.
The lecture will compare the copy number mutational landscape from one of the largest cohorts of children with developmental delay and multiple congenital abnormalities to that of normal adult individuals.
We searched the reports for single and multiple congenital abnormalities.
Of 3,110 cases reported as having orofacial clefts, 653 had multiple congenital abnormalities.
An ongoing pregnancy occurred but was terminated at 20 weeks' gestation because of multiple congenital abnormalities.
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On autopsy, the patient had evidence of multiple minor congenital abnormalities including a notched right atrial appendage (RAA) with recent mural thrombus (Fig. 4), medial displacement of the coronary sinus ostium, and an abnormally positioned Eustachian valve.
Further comparison of τ did not identify any significant influence of multiple pregnancies, congenital abnormalities, period of delivery, country's economic wealth, inclusion of secondary hypertension, maternal age, parity, ethnicity, or study definition of chronic hypertension on the degree of heterogeneity (τ>0.2 for all subgroups) or proportion of women with adverse events.
Congenital circumferential skin creases may be an isolated anomaly or may be associated with multiple congenital anomalies and developmental abnormalities [ 3].
We exclude stillbirths and neonatal deaths, infants whose mothers have died, infants with congenital abnormalities, multiple births, and mother/infant pairs who migrate out of the study area permanently during the study period.
Children were excluded if they were premature (<37 completed weeks' gestation), one of a multiple birth, had major congenital abnormalities, if the mother had had severe postnatal illness, or if the family was unlikely to be living locally for the next two years.
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multiple congenital defects
multiple congenital malformations
multiple congenital disorders
various congenital abnormalities
several congenital abnormalities
multiple developmental abnormalities
many congenital abnormalities
multiple congenital anomaly
multiple skeletal abnormalities
multiple neurologic abnormalities
multiple congenital anomalies
multiple chromosomal abnormalities
multiple pathophysiologic abnormalities
multiple congenital tumors
multiple anatomical abnormalities
multiple organ abnormalities
multiple oculomotor abnormalities
multiple cerebellar abnormalities
multiple laboratory abnormalities
multiple congenital contractures
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