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T2DM is a complex metabolic/cardiovascular disorder with multiple pathophysiologic abnormalities.
In individuals with established type 2 diabetes, multiple pathophysiologic abnormalities have been shown to contribute to the disturbance in glucose homeostasis (24).
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There are multiple pathophysiologic mechanisms underlying abnormalities in circadian BP, most importantly abnormalities in sympathetic nervous system activity, salt and volume balance, and activation of the renin angiotensin system.
We propose that using the %IBW/ leptin curve can facilitate identification of true pathophysiologic abnormalities in eating-disordered individuals and provide a basis for the design of therapeutic interventions or monitoring of response to treatment.
The observation that patients with PHN experience various types of pain suggests that multiple pathophysiologic mechanisms are involved, which may include the peripheral and central nervous systems.
Due to the advent of new technology and the refinement of existing technologies, imaging's role has extended into the biological, functional, and hemodynamic diagnosis of multiple pathophysiologic processes.
PTB is a complex disease, potentially induced by several etiologic factors from multiple pathophysiologic pathways.
Finally, insulin does not directly address the pathophysiologic abnormalities that are characteristic of stress hyperglycemia [ 13].
With the realization that pathophysiologic abnormalities in AHRF involve surfactant abnormalities as well as inflammatory and vascular changes, it is not surprising that nitric oxide (NO) has been investigated as an adjunct to the multiple ventilatory strategies adopted in the management of this disorder.
More likely, MACE incidence represents multiple pathophysiologic mechanisms, independent of a prior history of CAD alone.
HDL cholesterol has been demonstrated to reduce the risk of atherosclerosis by multiple pathophysiologic mechanisms [ 35].
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