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Syndromes with genetically determined retinal diseases and concurrent multiple neurologic abnormalities are rare.
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Multiple animal studies cite neurologic abnormalities in offspring after in utero BPA exposures (Chapin et al. 2008; NTP 2008).
"Stroke patients usually present with multiple neurologic deficits," he said.
Results: Two (18%) patients had no observed neurologic abnormalities, 7 (64%) demonstrated mild deficits, and 2 (18%) had severe neurologic deficits.
All live-born infants were without evidence of neurologic abnormalities at the time of discharge.
The Tay-Sachs model showed no neurologic abnormalities, whereas the Sandhoff model was severely affected.
There were major neurologic abnormalities in 13%, cognitive delays in 30%, and hearing loss in 19% of the infants.
Patients often manifest with a variety of neurologic abnormalities, including cerebral edema, seizures, cognitive impairment, and psychiatric illness.
While most patients do not present with focal neurologic abnormalities, those who do present with such have common deficits based on location of the MCA territory involved.
Neurologic abnormalities were observed in 83% of children at baseline but only 35% of children at week 48 (P =.004), suggesting a benefit of treatment.
Conclusions: Certain patients with neuroblastoma associated OMA may achieve average-range neurobehavioral function in spite of residual neurologic abnormalities, with suggestion of continued improvement over time.
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