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Exact(5)

In particular, we have shown that the study of biomolecules traditionally named "unstructured" by NMR and XRD is feasible due to the ability to measure multiple conformations at a given time and to perform kinetic studies of conformational interconversion as a way to elucidate folding/unfolding pathways.

The broadening suggests that the protein is able to access multiple conformations at low pH, and the disappearance of peaks indicates that the sample is more dynamic.

An extra layer of complexity has been added considering that slipped DNAs can assume multiple conformations at the junction, including having unpaired nucleotides.

Nevertheless, we provide good evidence to assume that multiple conformations at the junction site in oligos would also play a role in larger plasmid systems and perhaps in vivo, but with the caveats stated above.

The presence of broad on-diagonal peaks, particularly for A1H8 and H2, in the aromatic region of the 2D spectra for r(A GGC UU 2 also suggests multiple conformations at 0 °C.

Similar(55)

Each of these proteins had large binding regions which offered ample room for the ligand to bind in multiple conformations and at multiple sites within the binding region of the protein.

This model also has a very short nonbonded collision (<2.5 Å) with its own symmetry mate, so we suspect that it does not represent a true conformation but only approximates the average chain path associated with a set of multiple conformations that allow reasonable packing at the interface.

Two-dimensional C C and C N correlations suggest that at low pH multiple conformations are populated as the spectra broaden and eventually disappear as the acidity is increased.

Such searches may include a database of multiple conformations or may generate the proposed matching conformation at search time.

This was attributed to the presence of multiple conformations of the 1, N-ϵdG adduct at neutral pH (32).

These results indicated that MPER is natively flexible, indicating that more than one structure is associated with neutralization and, at the same time, implying that multiple conformations of MPER immunogens may be favorable to the induction of bNAbs.

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