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They expose to multiple complications such as: infectious, traumatic and thrombo embolic complications [1].
One of the most important complications related to fracture fixation and osseous substitution is the appearance of infectious processes on the surface of the implanted biomaterials, which bring about multiple complications such as long hospitalization stays, complex revision processes, implant looseness and failure, the high cost of replacement surgery, and subsequent patient pain [3, 4, 5, 6].
This prolonged period of time can lead to multiple complications such as pin-tract infections, broken wires, and joint impairment.
IR-T2DM is of importance because it is associated with multiple complications such as cardiovascular anomalies [ 3].
Intracranial dynamics play a central role in healthy brain function because disturbances in the internal fluid environment of the skull can lead to multiple complications such as, among other things, hydrocephalus [ 1].
A high risk of multiple complications such as voluminous postsurgical edema (which by itself diminishes blood circulation in the surgical site), total, or partial resorption of the graft by lack of vascularization, wound dehiscence, and donor-site complications are commonly known to accompany these procedures.
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In line with other acutely ill medical patients, stroke patients often have multiple other complications, such as advanced age, immobility, obesity, and venous insufficiency.
These are highly dependent patients who need almost all activities of daily living performed for them; those requiring initial intubation will require weaning from the respiratory support and their immobility puts them at risk of multiple medical complications, such as venous thromboembolism and pneumonia.
SCD is associated with multiple acute and chronic complications such as painful vaso-occlusive events, cerebral vasculopathy, priapism, chronic kidney disease, acute chest syndrome (ACS) and pulmonary hypertension among others [ 5, 6].
Those special patients often require multiple attempts, which consequently cause complications, such as hemorrhage and hematoma [ 9].
The cost associated with complications, such as multiple gestation and birth, were also not included in calculations.
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