Biliary tract cancer (BTC), which includes multiple cancers, such as cholangiocarcinoma and gallbladder carcinoma, is difficult to treat.
Thus, deregulation of these enzymes is linked to multiple cancers, such as breast, prostate, lung and colon cancers [ 33- 37].
Human WFDC1 maps to chromosome 16q24, an area characterized by a frequent loss of heterozygosity in multiple cancers such as breast, prostate and liver.
In the clinical context, PDT has been successfully used to treat superficial lesions of multiple cancers, such as skin cancer, breast cancer, and head and neck cancers.
It has been shown that xCT is highly expressed in multiple cancers such as hepatoma, lymphoma, glioma and lung, colon, breast, prostate and pancreatic cancer cells, which renders xCT a potential drug target for cancer therapy [ 13].
H19 is an important lncRNA that play roles in the infertility [ 35] and multiple cancers such as breast cancer [ 36, 37], cervical cancer [ 38], liver cancer [ 39, 40] and bladder cancer [ 41].
It has been demonstrated that polymorphisms of the IL-10 gene are associated with multiple cancer, such as gastric cancer, non-small cell lung cancer and breast cancer [ 3, 17- 20], and our results indicating that the polymorphisms of IL-10 are associated with GBM.
Consistently, the expression of TAZ is elevated in multiple human cancers, such as invasive ductal breast cancer and glioblastoma (Bhat et al., 2011; Chan et al., 2008; Cordenonsi et al., 2011; Zhou et al., 2015a), implying the oncogenic roles of TAZ in human cancer development.
The differentiations in IL-8 expression level result in multiple human cancers, such as breast cancer, Hodgkin's lymphoma, and prostate cancer.
Previous studies showed that RXRα is overexpressed in multiple human cancers such as human prostate tumor, 7 breast cancer, 8 and thyroid tumor.
These regions contain clusters of tumor suppressor genes involved in multiple cancer types such as lung, kidney, breast, cervical, head and neck, nasopharyngeal, prostate and other carcinomas.
