Sentence examples for multiple clock genes from inspiring English sources

Over the past decade, multiple clock genes have been identified, and it is now generally accepted that the generation of circadian rhythms is based on transcription-translation feedback loops comprising the activation of multiple clock genes.

Recent studies have shown that intracellular circadian oscillations are the result of transcription-translation feedback loops arising from multiple "clock genes" [1], [10].

The mechanism depends upon the inhibition of multiple clock genes by TOC1, particularly the PRRs.

Here, we extend our previous model by including the repression of multiple clock genes by TOC1 and explore TOC1 effect on the clock.

We extended the mathematical model of the plant clock gene circuit by incorporating the repression of multiple clock genes by TOC1, observed experimentally.

The observed reduction in the expression of multiple clock genes by up-regulation of TOC1 could not be described by our previous model, where only LHY and CCA1 were affected by TOC1 [ 2, 3].

Multiple circadian clock genes, including Clock, Cry1, Cry2, Per3, and Rora, are significantly suppressed within two hours after an endotoxin-challenge and remain suppressed for up to 17 hours post-infusion [ 16].

The key roles played by GI are evident when analyzing the effect of gi mutants over leaf movement and gene expression rhythms of multiple clock controlled and flowering genes, including GI itself [21], [22].

The PERDKO mice showed loss of peripheral clock in the liver in animals maintained in a normal 24 hour light dark cycle, as evidenced by expression patterns of multiple core and output clock genes.

In complex with its dimerization partners, CLOCK or NPAS2, BMAL1 controls the expression of several clock genes and multiple clock-controlled genes (CCGs).

Inflammation has also been shown to disrupt the expression of circadian clock genes in multiple tissues, including astrocytes, spleen and synovium fibroblasts (Cavadini et al. 2007; Duhart et al. 2013).