Sentence examples for mouse model inhibition from inspiring English sources

In an allergic mouse model, inhibition of SPT with myriocin was also associated with the exacerbation of airway hyperreactivity, in recent work by Edukulla and Lindsley [66].

In a pneumococcal meningitis mouse model inhibition of complement factor 5 was shown to improve outcome [18].

In PDA mouse model, inhibition of FAK impairs cancer cells proliferation and leads to the decreased CAFs recruitment [ 100].

In an orthotopic human glioma mouse model, inhibition of miRNA-10b diminishes the invasiveness, angiogenicity and growth of the mesenchymal subtype-like glioma cells in the brain and significantly prolonged survival of glioma-bearing mice.

Rapamycin-induced autophagy was shown to suppress PD symptoms in a mouse model; inhibition of mTOR by rapamycin also increased the lifespan of mice by inducing a combination of increased autophagy and decreased mRNA translation (Rieker et al., 2011).

In mouse models, inhibition of GATA-6 during fetal life inhibited terminal differentiation of respiratory epithelial cells (Liu et al. 2002; Yang et al. 2002).

In mouse models, inhibition of the enzyme (ACAT1/2) attenuates both ATH and AD.

Although suppression of HDAC1 prolonged disease latency in APL mouse models, inhibition of HDAC1 (and HDAC2) would accelerate APL pathogenesis in the early transformation stage owing to its effect on the expansion of a subset of APL cells with leukaemia-initiating features (Santoro et al, 2013).

Additionally, in the B16-F10 melanomalanomodeldel, inhibition of MIF by RNAi significantly delayed tumour establishment when injected into mice [ 27].

This presentation might lead to activation or - as recently described in a mouse model - inhibition of T-cell responses [ 37].

In an arthritis mouse model, sclerostin inhibition resulted in a decrease in the loss of bone mass [ 31, 32].