Sentence examples for mouse model deficient from inspiring English sources

We chose the Rag1-/ mouse model deficient in both mature T and B lymphocytes [23].

The Müller glial cell-targeted gene transfer was tested in a mouse model deficient for Crumbs homologue 1 (CRB1) that exhibits retinal degeneration accompanied by Müller cell gliosis.

We present the first evidence from a mouse model deficient in ankyrin-B that ankyrin-B variants can be viewed as balanced variants with increased risk of sudden death and early aging offset by increased cardiac contractility.

Overall, this study presents an optimized approach to globally monitor cystatin gene expression as well as a new mouse model deficient in Stfa2l1/Csta genes, expanding the available tools to dissect cystatin roles under normal and pathological conditions.

Consequently, we used a new mouse model deficient for Card15/Nod2 i) to evaluate the involvement of Nod2 on the number and PPs size; ii) to assess whether Nod2 modified cellular composition and cytokine expression of PPs; and iii) to determine whether Nod2 may alter paracellular permeability and bacterial translocation of PPs in adult mice.

Here, we describe a novel mouse model deficient in SAFB2.

So far, no mouse models deficient in Fam162a, Ccdc58, Csta, or Stfa2l1 have been described.

The spermatocytes in defective Ing2−/− seminiferous tubules underwent meiotic arrest (Fig. 2G), which was also observed in mouse models deficient for histone methyltransferases [10], [11], [12].

Recently, the function of AAMs was addressed either by depleting them or by using mouse models deficient in their signature molecules like Arg1 and Fizz1.

The thymopoietic phenotypes of Cdc42−/− mice are reminiscent of and complementary to the previous observations in mouse models deficient in Rac1, Rac2 or RhoH, other members of Rho family GTPases.

Increased DA levels in the absence of neurodegeneration were also reported for PD mouse models deficient only in Parkin (PARK2) [32] and in some in vitro studies of A53T-SNCA [20], [33], [34].