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FY contributed ideas in protein extraction and mouse model establishment.
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Although the existing humanized mouse model begins to allow establishment of infection models of human pathogens, such as HIV, the current system is far from optimal.
The use of antibodies [ 4- 7], antisense targeting [ 8] and inhibitors [ 9, 10] has proven useful in inhibiting the establishment, progression and metastasis of tumors in mouse models, thereby establishing ANG as a promising target for anticancer therapy.
Monteiro, A. C. et al. T cells induce pre-metastatic osteolytic disease and help bone metastases establishment in a mouse model of metastatic breast cancer.
The establishment of a mouse model is of great importance, as the availability of diverse immune-deficient mouse models could deliver more insight into immunological processes of radiation nephropathy in prospective studies.
Furthermore, establishment of a mouse model for anthrax meningitis will aid in our understanding of disease pathogenesis and development of more effective treatment strategies.
Therefore, attention has focused on mouse models [ 12, 13], and establishment of a mouse model for stomach cancer featuring salt and H. pylori exposure is needed for investigations targeting genes involved in gastric carcinogenesis.
An intraperitoneal inflammation decreases endometriosis establishment in this mouse model.
This study investigates the impact of a pre-existing peritoneal inflammation on endometriosis establishment in a mouse model.
Our data demonstrated the establishment of a mouse model of interstitial pneumonitis via MCMV infection after allogeneic skin transplantation.
The present study addresses one aspect of this 'chicken or egg' question, analysing the influence of a pre-existing peritoneal inflammation on endometriosis establishment in a mouse model.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com