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It's a trillion gigabytes of data to do an entire mouse brain, where I get every connection between every neuron, is going to require a trillion gigabytes of data.
These phenotypes are consistent with the expression patterns we have identified in mouse brain where Jarid1c mRNA was detected in hippocampus, hypothalamus, and cerebellum.
This is in line with analyses of the mouse brain, where cytosolic PrP was detected in neurons of the neocortex and hippocampus, but not the cerebellum [20], [21], and suggests that cell-specific factors influence PrP translocation.
This contrasts with a recent SAGE study of P30 mouse brain, where the number of matched GenBank transcripts with copy number five or more per cell was 4,161 [17], but those data lacked the allele-specific identification.
The presence in SH-SY5Y cells of endogenous alkaloids in LDC vesicle-like structures, their release by a Ca2+-dependent exocytotic mechanism, and their effects on these cells at concentration as low as 0.1 nM led us to investigate whether endogenous morphine may represent a neuromodulator in the mouse brain, where M6G is absent [31].
Since there is no suitable antiserum available for immunocytochemistry against chick cyclin D that allowed to test the expression in interphase G1, the coexpression of cyclin D and Delta1 in NP cells was assayed in preneurogenic regions of the developing mouse brain where Delta-1 expression has been also observed in scattered cells [30].
Similar(50)
A similar result was found for embryonic mouse brains, where the majority of PS1, nicastrin (part of the secretase complex) and APP CTF remains soluble in Lubrol-WX [ 50].
Moreover, we compared the β-globin locus in two different biological samples (mouse primary erythroid cells and mouse fetal brain), where it is either actively transcribed or not, to identify possible transcriptional dependent interactions.
In Nature Medicine today, Wyss-Coray's lab at Stanford and Saul Villeda and co-workers at the University of California, San Francisco, report that parabiosis can rejuvenate another part of the mouse brain, the hippocampus, where memories are made and stored.
The activation of STAT-3 in response to cigarette smoke appears to be a robust response demonstrated in a variety of tissues including human bladder cells lines [ 132], human bronchial epithelial cell lines [ 133], and mouse brain endothelial cells where it has been associated with the regulation of antioxidant defense response [ 134].
An exception was found in human and mice brain cells, where non-CG methylation is highly conserved in regions with low CpG-density, and likewise to mCG represses gene transcription [ 25, 26].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com