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Headache is described as migraine like in the ICHD-II, but in most published cases the description is non-existent or poor [2].
Tibial tubercle osteotomy during RTKA has provided good clinical results in most published cases.
In most published cases of 46,XY DSD due to NR5A1 mutations, testosterone has been low indicating significantly impaired androgen synthesis.
In most published cases, all data given in the publication would be acceptable to include in the database, including geographical location and ethnic group of individuals studied (both for cases and for population controls) and clinical details of patients.
The ~44% level of proteome coverage is in line with, and in most published cases exceeds, results obtained in both typical proteomics experiments [ 25- 27] and previous proteogenomic analyses [ 17, 28, 29].
In the case of severe acute hepatitis following introduction of intravenous amiodarone, liver enzyme abnormalities occur within hours to days of treatment initiation and although most published cases were reversible after discontinuation of the treatment, acute liver failure and death have been reported.
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Most published case series studies on FEA used a small number of cases, ranging from three [ 32] to six [ 11] or eight [ 18], which might have contributed to the reported contrasting results.
3 4 In agreement with most published case-control studies 2 we observed significantly fewer subsequent diagnoses in patients who had undergone appendicectomy, the association being restricted to appendicectomies for appendicitis or mesenteric lymphadenitis before the age of 20.
First of all, because the clinical symptoms and excellent outcomes observed in the affected patients are at odds with most previously published cases.
Most of the published cases deal with QSAR models resulting from academic studies, for instance those studying a certain relationship between toxicity and a descriptor, proposing new descriptors as tools to better capture chemical structures, or describing a new algorithm to explore the possible links between toxicity and descriptors.
The engagement was feasible in most of the published cases we found, but faced several challenges and barriers.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com