Sentence examples for most potent suppressor from inspiring English sources

Oligo-166 was identified as the most potent suppressor of SNCG expression in LNCaP cells.

PMA, an activator of PKC, is the most potent suppressor of GC-B activity currently known [ 21, 24].

KRAB, the most potent suppressor in our system, does not affect the status of DNA methylation in the promoter.

A screen of genetic regulators of toxicity due to a mutant huntingtin fragment in S. cerevisiae identified Bna4 (kynurenine 3-monooxygenase) as the most potent suppressor [ 50].

Polyethylene-glycol (PEG) is a strong inhibitor of colon cancer in rats, and the most potent suppressor of aberrant crypt foci.

The number of CD4+CD25highFoxp3+ cells represent 1-21-2% totalotal CD4+ circulating cells, which is the most potent suppressor subset of Tregs for the maintenance of immune tolerance and homoeostasis, as related to hypertension during pregnancy.

Judging from the EC50 values, antisense PNA oligomers targeting regions 24 38 EC50 = 700 nM) or 27 38 EC500 = 80 nM) were the most potent suppressors of protein expression.

One of the most potent suppressors of immune responses is UV irradiation.

For example, triethyltin bromide, which is already known to interrupt ATP production, also proved to be one of the most potent suppressors of MMP.

A subsequent genetic screen confirmed the importance of oxidative stress and a molecular dissection of the steps in the cellular metabolism of reactive oxygen species revealed that the iron-binding protein ferritin and the H2O2 scavenger catalase are the most potent suppressors of the toxicity of wild-type and Arctic (E22G) Aβ1–42.

Although Smad4 is the most potent tumor suppressor, its functions are highly context-specific as exemplified by pancreatic cancer and head-and-neck cancer: in pancreatic cancer, Smad4 loss cannot initiate tumor formation but promotes metastases while in head-and-neck cancer Smad4 loss promotes cancer progression but also initiates tumor formation, likely through effects on genomic instability.