Sentence examples for most important loci from inspiring English sources

In addition to selecting the most important loci and determining statistical significance, several other areas of uncertainty remain.

RA is a polygenic disease and its most important loci are in the major histocompatibility complex (MHC).

First, more work is needed to determine the best approach for selecting the most important loci in the NN [ 4, 18, 19, 24].

One of the most important loci of genetic polymorphisms linked to bipolar disease and depression is around the ATP-activated ion-channel receptor P2X7.

A wide variety of somatic gene variations may hinder us from easily finding the most important loci contributing to NPC genesis.

Our results suggest that congregate settings, the focus of our program, are the most important loci of TB transmission among homeless persons.

The way in which dominance is established is perhaps the most important locus of disagreement concerning Kuhn's work.

First, [the credibility thesis] explicitly assumes that the commitment of the NWS [nuclear weapons states] to the ideal of disarmament lacks credibility, and implicitly assumes that the United States is both the most important locus of the problem and the key to its resolution.

Single nucleotide polymorphisms (SNPs) of TCF7L2 have been consistently associated with T2DM in populations of different ethnic descent, making TCF7L2 one of the most important locus known today to predispose for T2DM [7]–[9].

Families are the single most important locus of care and protection for children (American Academy of Pediatrics, 2003), and children are inextricably dependent on the resources, capacities and well-being of families.

The next most important locus is that of the insulin (INS) VNTR (variable number of tandem repeats), which is of considerable interest because insulin has been proposed as the key antigen initiating the process of autoimmunity [ 9].