Sentence examples for more terminal differentiation from inspiring English sources

BrdU staining showed that 40.34±2.193 of CD56+ cells and 52.44±3.691 of CD56− cells (p = 0.048) were in S phase 3 days after plating in proliferative medium, another indication that the CD56+ sub-population might be undergoing slightly more terminal differentiation than CD56− cells (Figure 6c, h, i).

Larger CMV-specific responses go together with a more terminal differentiation phenotype of all T-cells (fewer naive and more cells of advanced differentiation phenotype, particularly in central and effector memory compartments) (Lachmann et al., 2012).

We collected our data before 96 hours by which time early stages of differentiation, such as early neural differentiation, may be tracked, but more terminal differentiation to heart, brain, liver, kidney has not yet taken place.

In older donors, the memory phenotype of tuberculin-induced T-cells was significantly skewed towards a more terminal differentiation phenotype in CMV-infected compared to uninfected individuals and the degree of skewing correlated quantitatively with the size of the CMV-specific CD4 T-cell response.

As CMV is known to drive the whole T-cell compartment towards a more terminal differentiation stage (Fletcher et al., 2005), we wondered if phenotype and functionality of the tuberculin-specific response in older people would be affected by CMV-status, phenotype or functional profile of the CMV-specific T-cell response.

Hypertrophy was remarkably inhibited with PTHrP treatment, though the OA cells were more inclined to terminal differentiation.

There are two PPARγ isoforms generated by alternative splicing, PPARγ1 and PPARγ2, being PPARγ2 more efficient to induce terminal differentiation in vitro [28].

Multicellular patterns comprise basic filamentous forms as found for section III, as well as more complex forms involving terminal differentiation, present in sections IV and V.

Comparing immersed epidermal cultures with cultures incubated at the air liquid interface, that study interestingly described important roles of several molecules from different, sometimes unexpected, metabolic pathways in establishing the fully differentiated phenotypes, proving that the process of terminal differentiation is more complex than a process involving structural molecules only [ 22].

At the same time, stem cells need to generate more differentiated cells that ultimately undergo terminal differentiation.

Therefore, these results let us to speculate that the chromatin state of cell cycle regulatory genes might be more permissive for transcription upon terminal differentiation in vitro rather than in tissues in vivo.