Sentence examples for more terminal phenyl from inspiring English sources

For example, homologues with the same molecular weight (i.e., same number of carbons in the alkyl chain) but with a more terminal phenyl position (e.g., the 2-phenyl position) will be more toxic than homologues with a more central phenyl position (e.g., 5-phenyl position).

In addition, compounds with mono-methoxy group at the 3-position or dimethyl groups at the 3,5-position on the terminal phenyl ring were more active.

The SAR analyses indicated that compounds with mono-halogen groups at 4-position on the terminal phenyl ring were more active than those with double-halogen groups or methyl groups.

Since the smaller compounds did not show sufficient activity we moved the focus to explorations on the terminal phenyl ring (Table 2).

The crystal structure also predicts a non-classical hydrogen bond between the hydroxyl group of Thr63 (H-bond donor) and the fluorine of the terminal phenyl group (H-bond acceptor).

To improve the metabolic stability, several linker modifications were attempted as replacement of amide linker along with different phenyl or other heteroaryls between C8 position of xanthine head group and terminal phenyl ring.

The study of structure-activity relationships also revealed that a suitable substitution on para-position of terminal phenyl ring was crucial for high activity.

Their preliminary structure-activity relationships (SARs) studies indicate that electron-withdrawing groups on the terminal phenyl rings are beneficial for improving the antitumor activity.

Various substitutions on terminal phenyl group and different alkyl substitutions on N-1 and N-3 were explored to improve the potency, selectivity for A2BAdoR and the solubility.

The incorporation of heterocyclic replacements of the terminal phenyl D-ring of lead compound 1 was conducted in order to align potency with favorable drug-like properties.

We have explored the optimal substituents on the terminal phenyl ring of the 3-phenoxybenzylidene moiety in 27, by generating a set of six analogs.