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The present study shows that the intensity of sarcoidosis expressed by the maximum SUV is a more significant prognostic indicator than metabolic volume, which reflects the extent of inflammation.
In this respect, BM sampling after surgery was expected to give more significant prognostic information.
We demonstrated that BMP-7 expression was a more significant prognostic factor only in the undifferentiated group.
Zhang et al. [ 32] reported that EGFR had more significant prognostic value than CK5/6 in the study of 136 TNBC patients.
It is considered more neoangiogenesis-specific than pan-endothelial CD34 and CD31 antibodies and might have a more significant prognostic value for some cancers [ 14, 17, 18].
This suggests that HER2 expression may be a more significant prognostic factor than PR loss in tumors with HER2 overexpression (HER2+) or may be associated with the results of trastuzumab treatment.
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Altogether, the above results show that the miRNA-target modules, which are the set of proteins targeted by one or more miRNAs, are significant prognostic modules for prostate cancer.
Sub-analysis of the lymph node positive group revealed nodal burden (where high burden was regarded as four or more positive) was a significant prognostic factor (P=0.0004).
Cheze-Le Rest et al. investigates a total of 52 patients with all stages of disease; performance of potentially curative surgery, SUVmax >9 and 2 or more PET abnormalities were significant prognostic predictors.
Within this cohort, BCI is a highly significant prognostic tool, identifying more than 50% of patients as low-risk [ 6].
This issue is certainly of more translational relevance, and may add significant prognostic value to the currently used indicators for outcome prediction in breast cancer progression.
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