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Further studies will be required to determine whether measurement of change in LIS is a more useful prognostic indicator as has been previously suggested [57].
Moreover, the combination of CA 19-9 and other tumor markers provided more useful prognostic information.
More useful prognostic factors are clearly required to identify patients with poorly managed DLBCL.
Nevertheless, the visual reading of PET response after two cycles gave more useful prognostic information (HR 43.82, P < 0.0001) than the corresponding SUV measurement (HR 1.131, P = 0.001).
Further studies will be required to determine whether measurement of change in LIS is a more useful prognostic indicator as has been previously suggested [ 57].
Thus, overexpression of FGF receptor may prove to be a more useful prognostic marker than basic FGF expression level in pancreatic cancer patients.
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Volumetric metabolic parameters may be more useful as prognostic factors in patients with SCLC of LD rather than of ED.
Therefore, the volumetric PET parameters may be more useful as prognostic factors in patients with LD rather than ED.
Identifying the genes involved, and epigenetic factors, perhaps will allow development of a more useful and prognostic classification system in the near future.
Since many elderly patients present with fewer signs and symptoms and several cases are marked by atypical presentations, biomarkers often become more useful than prognostic scoring [ 18, 19, 67].
Admission values are potentially more useful as prognostic markers, if they can be made available to the clinician at the time the patient is first seen, as they could help to identify a group of patients requiring aggressive treatment or characterize those eligible for entry to a randomized clinical trial of adjunctive therapies.
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