Sentence examples for more severe disruption from inspiring English sources

We reasoned that if the Tl→dl pathway is a key player in Aβ42 induced neurodegeneration, then it would be possible to ameliorate even this much more severe disruption in eye development by reducing dl activity.

This may be a reflection of differences in the degree of fragmentation (perhaps more severe disruption is evident in the isolates than fissioned mitochondria in vivo), or other factors related to the process by which the mitochondria are mechanically homogenized, as discussed in the next paragraph.

Further assessment of various disease risk factors and their associated cognitive effects may lead to better identification of those children most at-risk for more severe disruption.

The alterations were dependent on the time of cell administration, significant morphological changes took place 15 weeks after cell administration, and a more severe disruption of the alveolar walls occurred after 30 and 60 weeks.

Because of its critical positioning, the mutation of R179 might cause a more severe disruption of actin polymerization than other mutations, which may explain the more severe and generalized phenotype reported for R179 mutations [ 12].

Treatment of starved Fabry disease fibroblasts and lymphocytes with lysosomal protease inhibitors reveals a block in autophagic flux, demonstrating a more severe disruption of degradation through macroautophagy than that observed in other sphingolipidoses.

As explained above, residential region and obstetrical care after the disaster were a focus of the current study due to previous investigations reporting a higher frequency of depressive symptoms in areas that experienced higher radiation levels within one city [ 9], and more severe disruptions of obstetrical care immediately following the disaster [ 6].

Those females (n = 30) identified as outliers are listed in Supplementary Material, Table S9 and were excluded from further analysis as the increased degree of escape from XCI appeared to occur in samples with a consistent, chromosome-wide, lower level of DNAm, which raised concerns of more severe disruptions in DNAm.

"Today Libya is facing an even more severe internet disruption, yet we continue to see the movement picking up pace.

The potential for more severe climatic disruption is real enough as the large pools of carbon from forests, tundra and their soils are mobilized by the rapid warming intrinsic to the high latitudes.

The president said he was prepared to open the spigot on the 727-million-barrel Strategic Petroleum Reserve if there were a sudden and more severe supply disruption than has occurred to date.