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Therefore, small molecules specifically designed to inhibit the FucT-VII enzyme may have potential as anti-inflammatory agents.
Gold coated cantilevers are initially functionalized with tetraTTF-calix[4]pyrrole molecules, specifically designed to bind nitro-aromatic compounds.
Membrane lipid therapy proposes the use of new molecules specifically designed to modify membrane lipid structures and microdomains as pharmaceutical disease-modifying agents by reversing the malfunction or altering the expression of disease-specific protein or lipid signal cascades.
Here we describe the identification of the first small molecules specifically designed to inhibit the HIV-1 replication by targeting the RNA binding site of the human DEAD-Box RNA helicase DDX3.
Chemosensors are molecules specifically designed for the qualitative and quantitative monitoring of analytes and are being researched in the areas of biological and analytical chemistry, medicine and environmental sciences (Bell and Hext 2004; Minkin et al. 2008).
Similar(55)
Here we report on an attempt to do this with the surprising result that a molecule specifically designed to display SMM behaviour proves not to, posing the question as to why this should be.
The present study validates the approach of using a short dsRNA molecule specifically designed with a single guide strand to suppress the expression of multiple unrelated genes implicated in a particular medical condition.
Anecortave acetate is a cortisene molecule, specifically designed to retain the anti-angiogenic properties of corticosteroids while eliminating the aforementioned side-effects and is administered as a posterior juxtascleral depot injection every 6 months (AAC 2003).
These molecules were specifically designed as MAH substitute able to limit the iPP degradation, while providing functionalisation through grafting.
A more reliable method for controlled switching and stabilized conductance states has been demonstrated using the applied electric field and the stabilizing effects of hydrogen-bonding interactions between the active molecules and a specifically designed matrix; however, for the purposes of this work, we have shown examples using only electric field.
The anti-replicative strategy aims to induce such a shift in heteroplasmy by mitochondrial targeting specifically designed molecules in order to inhibit replication of mutant mtDNA.
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