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Novel therapeutics strategies comprise multifunctional compounds specifically designed to target concurrently on different sites at multifactorial etiopathogenesis of AD, thereby providing greater therapeutic efficacy.
Chemical synthesis opens the door for the production of compounds specifically designed to maximize effectiveness and improve bioavailability.
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Herein we evaluate the therapeutic efficacy of a novel α-emitting compound specifically designed for intracavitary radiation therapy.
Most auto parts suppliers carry a "lapping/polishing compound" specifically designed for headlight exteriors.
Similar results were noted for a related series of oligomeric model compounds that were specifically designed to mimic local monomer sequences present within the larger polyester structures.
Etravirine is a diarylpyrimidine compound that was specifically designed to bind to HIV-1 reverse trancriptase in a more flexible manner than efavirenz and nevirapine and to require more than one key NNRTI resistance mutation for resistance development 37– 39(ie, to possess a higher genetic hurdle to resistance).
Our screen was specifically designed to identify compounds that elevated transgenic insulin reporter activity in larval zebrafish.
Based on the ubiquitin proteasome system (UPS), we have devised a protein knockdown system for inducing the selective degradation of target proteins by using specifically designed hybrid small compounds.
Pharmaceutical active compounds (PhACs) are persistent during the process used to treat drinking water and, because drinking water treatment plants are not specifically designed to remove PhACs, these compounds are found in drinking water.
MP-MUS, the lead compound in a family of pro-drugs specifically designed to treat GBM, is converted to the mature drug P+-MUS by the enzyme MAOB.
Gold coated cantilevers are initially functionalized with tetraTTF-calix[4]pyrrole molecules, specifically designed to bind nitro-aromatic compounds.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com