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Recent reports have provided evidence that magnolin inhibits the expression of cell adhesion molecules including intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 [ 38].
IL-1β induces the expression of adhesion molecules, including intercellular adhesion molecule-1 and vascular cell adhesion molecule-1, on mesenchymal and endothelial cells [ 39- 42].
Cell adhesion molecules including intercellular adhesion molecule-1 (ICAM-1), vascular adhesion molecule-1 (VCAM-1) and E-selectin are the biomarkers of endothelial activation [ 43].
In addition, 15-HETE prevents polymorphonuclear neutrophil migration across IL-1β or TNF-α-activated endothelium [ 32] and TNF-α-induced expression of several adhesion molecules, including intercellular adhesion molecule-1, vascular cell adhesion molecule-1 and E-selectin [ 33].
Blood vessels in both psoriatic skin and synovial tissue express a variety of adhesion molecules, including intercellular adhesion molecule (ICAM -1, vascular cell adhesICAM -1cule (vascular and E-selecell [ 13, 19].
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Cell adhesion molecules (CAMs), including intercellular adhesion molecule-1 (ICAM-1) and vascular adhesion molecule-1 (VCAM-1), which are expressed by activated endothelial cells, play a crucial role in leukocyte adhesion and migration [2], [3].
Several cell adhesion molecules (CAMs), including intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) have been implicated in cancer growth, and metastasis [ 19, 20].
Cellular infiltration into the pancreas correlated with increased expression of adhesion molecules on pancreatic endothelium, including intercellular adhesion molecule 1 (ICAM-1) [10].
Various adhesion molecules have been identified on endothelial cells, including intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) [ 2].
An increase in the serum levels of soluble adhesion molecules including soluble intercellular adhesion molecule 1 (ICAM-1) and soluble E-selectin are found in SSc patients compared with controls, and these correlate with tissue expression of endothelial adhesion molecules and severity of disease manifestations.
13– 18 Several studies have shown that irradiation of human and murine tumor cell lines upregulates the expression of numerous immunologically relevant molecules – including Fas, intercellular adhesion molecule-1, and the human carcinoma-associated antigens, carcinoembryonic antigen and mucin-1, cell surface associated – which may make them better targets for immune recognition.
Related(15)
genes including intercellular
molecules including extracellular
molecules including classical
molecules including simple
molecules including many
molecules including non-polar
molecules including folded
molecules including other
molecules including potential
molecules mediating intercellular
molecules including fatty
molecules including pro-inflammatory
molecules including aromatic
molecules including biological
molecules including large
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